According to Bloomberg, they've had enough,
“We are going to get engaged,” said Scott Reed, senior political strategist for the U.S. Chamber of Commerce. “The need is now more than ever to elect people who understand the free market and not silliness.”As the article points out, the Chamber spent $35.7 million on Federal Elections in 2012. But the Chamber might be in a position to exercise influence beyond their own spending by pressing their members to stop funding those groups that fund the tea party, such as FreedomWorks, Club for Growth, Senate Conservative Fund, Heritage Action, etc.
In fact, this might already be happening. According to BuzzFeed, FreedomWorks is cash strapped and seeking emergency funding.
The next several election cycles are going to be interesting. And better them than us.